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CCG-1423 represses SRF and p49/STRAP. (A–C) C2C12 cells were treated with a 10 µM dosage for 24 h. (A) The mRNA expression of SRF and p49/STRAP was evaluated in qPCR. DMSO was used as control. Immunoblotting was used to evaluate the protein levels of (B) SRF and (C) p49/STRAP. GAPDH was used as the total protein loading control and relative protein expression was quantified in (B,C). ** p < 0.01, **** p < 0.0001 (n = 3).
