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. 2022 Sep 24;23(19):11255. doi: 10.3390/ijms231911255

Figure 2.

Figure 2

Modulation of AhR either by deletion or AhR agonist (omeprazole) in the nerve explant culture. Nerve explant either from wild or AhR-deleted mice was harvested and subjected to different treatment profiles observed on day-3. (A) Representatives of ovoid number in a light microscope related to different treatments. (B) Representatives of AhR in different treatments. (C) The expression of S-100 in different treatment groups. (D) The expression of NF-II in the different treatment groups. (E) The expression of NGF in different treatment groups. (F) The expression of TNF-α in different treatment groups. (G) The quantitative analysis of the target proteins in the different treatment groups. N = 3, Bar length = 100 μm, omeprazole concentration: 30 μM, *: p < 0.05; **: p < 0.01; ***: p < 0.001 indicated the value related to the group of Wild type-CCI. Wild type-sham; Wild type-CCI; AhR (−/−)-CCI; Wild type-CCI-omeprazole; AhR (−/−)-CCI-omeprazole: see text. # and ## indicated the value of wild type-CCI-omeprazole realtive to wild type-CCI.