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. 2022 Sep 29;23(19):11518. doi: 10.3390/ijms231911518

Table 2.

HNT nanocomposites for controlled and sustained anticancer drug delivery.

Anticancer Drug Cell Type HNT Modifications Reference
Anthocyanins MCF-7, HT-29 HNT-Anth [114]
Atorvastatin Caco-2, HT-29 HNT-ATV@HF-CEL [115]
Camptothecin HeLa f-HNT/CPT and Fmoc-F/f-HNT/CPT [116]
Camptothecin Caco-2 CPT@COS/MHNTs and
CPT@FA-COS/MHNTs
[117]
Curcumin Caco-2 HNT-APT-PMVEMA@MF [118]
Curcumin HepG2, MCF-7, SV-HUC-1, EJ, CaSki, HeLa HNT-COOH/Chitosan [119]
Curcumin SUM 149, MDA-MB-231, HL60, HL60R f-Hal-1, 2, 4, 5, 6, and 7 [120]
Curcumin MCF-7 PCL/PEO-Cur/HNT, PCL/PEO-Cur/HNT-GPTMS, and
PCL/PEO-Cur/HNT-APTES
[121]
Doxorubicin MCF-7 DOX@HNTs-g-COS [122]
Doxorubicin A549 DNA-wrapped HNTs [123]
Doxorubicin SKOV3, 293T DOX@HNTs-S-S-β-CD-Ad-PEG-FA [124]
Doxorubicin MCF-7 DOX@HNTs-PEG-FA [125]
Doxorubicin HeLa DOX loaded Fe3O4@HNT [126]
Doxorubicin MCF-7 Au-HNT-DOX@BSA-FA [127]
Doxorubicin MCF-7, COLO 205 HNT-liposome-coated surfaces [128]
Doxorubicin HeLa, MCF-7 HNTs-DOX conjugated
with anti-EpCAM antibody
[129]