Figure 1.

Selective anti-CSC activity of screened drugs in CSC and non-CSC MDA-MB-231 cells grown under attachment conditions. (A) IC₅₀ values for each compound in both subpopulations after 72 h of incubation. (B) Representation of IC₅₀ of compounds that showed a greater cytotoxic effect against CSCs compared to non-CSCs. Differences were statistically significant (** p < 0.01) when comparing IC₅₀ values of 8Q and NCS between both cell subpopulations, but not in the case of SAL. Data are represented as the mean ± SEM of three independent experiments.