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. 2022 Oct 4;23(19):11760. doi: 10.3390/ijms231911760

Figure 3.

Figure 3

Efficacy of 8Q and NCS inhibiting migration, tumorigenicity and invasion in MDA-MB-231 cell line. (A) Wound healing assay showing the percentage of open wounds after 8 and 24 h of treatment with 1 µM PTX, 25 µM 8Q and 0.5 µM NCS. (B) Representative images of the wound closing over time. The wound area has been outlined in black and pseudocolored in gray. (C) Cell growth in soft agar (anchorage-independent growth) upon treatment with different concentrations of PTX, 8Q and NCS. (D) Rate of cell invasion in Matrigel after 24 h treatment of 1 µM PTX, 25 µM 8Q and 0.5 µM NCS. All graphs show the mean ± SEM of at least three independent experiments. All statistical analyses were performed compared to the control non-treated cells (** p < 0.01, *** p < 0.001, **** p < 0.0001).