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. 2022 Sep 23;23(19):11215. doi: 10.3390/ijms231911215

Figure 4.

Figure 4

DPDS enhanced the gene expression of Nrf2 and antioxidant enzymes in t-BHP-stimulated HBZY-1 cells. HBZY-1 cells were incubated with t-BHP (400 μM) alone or in combination with indicated concentrations of DPDS for 24 h. The relative mRNA levels of Nrf2 (A), NQO1 (B), HO-1 (C), GCLC (D), GPX1 (E) and Keap1 (F) expressed as fold of the t-BHP group. Gene levels were normalized against those of β-actin. Values are presented as means ± SEM, n = 3–4. * p < 0.05, ** p < 0.01 versus the 400 μM t-BHP group.