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. 2022 Sep 21;23(19):11068. doi: 10.3390/ijms231911068
aa Amino acid residue
ADP Adenosine diphosphate
ALL Acute lymphoblastic leukemia
APC Antibody-PROTAC conjugate
AR Androgen receptor
Arg Arginine
BC Breast cancer
BCR B cell receptor
BET Bromodomain and extra-terminal domain
BRD4 Bromodomain-containing protein 4
BTK Bruton’s tyrosine kinase
CDK Cyclin-dependent kinase complexes
CDK6 Cyclin-dependent kinase 6
CDK9 Cyclin-dependent kinase 9
CLIPTAC In-cell click-formed Proteolysis Targeting Chimeras
CML Chronic myeloid leukemia
CRBN Cereblon
CRC Colorectal cancer
DHT Dihydroxytestosterone
DNA Deoxyribonucleic acid
EGFR Epidermal growth factor receptor
ERRα Estrogen-related receptor α
FDA Food and Drug Administration
HECT Homologous to the E6AP carboxyl terminus
HER 2 Human epidermal growth factor receptor 2
HIF1α Hypoxia-inducible factor-1α
HSP-90 Heat shock protein 90
IAP Cellular inhibitor of apoptosis protein 1
LK-Ph+ Philadelphia chromosome positive chronic myeloid leukemia
mAb Monoclonal antibodies
MCL1 Induced myeloid leukemia cell differentiation protein
MDM2 Mouse double minute 2
MeBS Bestatin
MetAP-2 Methionine aminopeptidase-2
MM Multiple myeloma
mRNA messenger RNA
Mut Mutant
NAD+ Nicotinamide-adenine dinucleotide
NHL Non-Hodgkin’s lymphoma
NSCLC Non-small cell lung cancer
PARP1 Poly (ADP-ribose) polymerase-I
PARPs Poly (ADP-ribose) polymerases enzyme
PC Prostate cancer
PDP Protein Degradation Probe
PEG Polyethylene glycol
PIK3C3 Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3
PKB Protein kinase B
POI Protein of interest
Poly-Ub Polyubiquitin
PROTAC PROteolysis-TArgeting Chimera
PROTAP PROteolysis TArgeting Peptide
RARα Retinoic acid receptor alpha
RBR RING1-in-between-RING 2
RING Really Interesting New Gene
RNAi RNA interference
Ro5 Lipinski’s Rule of Five
SARM Selective androgen receptor modulator
SMI Small molecule inhibitors
SNIPPER Specific and Non-genetic IAP-dependent Protein ERaseR
TNBC Triple negative breast cancer
TPD Targeted protein degradation
TrkC Tropomyosin receptor kinase C
Ub Ubiquitin
USP Ubiquitin-proteasome system
VHL Von Hippel-Lindau