Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 23;23(19):11209. doi: 10.3390/ijms231911209

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fractionation of FRBA using a Sep-Pak Plus C18 cartridge resulted in fractions D–G, some of which possess the ability to reduce the inflammatory reaction of LPS-treated RAW 264.7 cells. (A) FRBD did not affect the expression of Il-1β, Il-6, or Tnf-α; (B) FRBE decreased the mRNA levels of Il-1β, Il-6, and Tnf-α; (C) FRBF reduced the expression of Il-1β and Il-6; (D) The FRBR treatment did not affect the mRNA levels of the pro-inflammatory cytokines in the LPS-activated RAW 264.7 cells. The data are represented as mean ± SE, n = 3. Significant differences between the LPS group and the other groups (Dunnet’s analysis, p < 0.05) are marked with asterisks (*).