Figure 2.

General modulation of retinal inflammation by nicotinamide mononucleotide (NMN) treatment in mice. (A,B) Representative pictures and quantitative analyses (n = 5–6 per group) demonstrated that the number of retinal I/R injury-induced IB4 positive inflammatory cells in the retina was reduced by NMN injection 5 days after injury. Scale bar: 50 μm. White boxes, enlarged pictures; Stars (*) in enlarged pictures, IB4 positive inflammatory cells. ** p <  0.01 and # p <  0.05. One-way ANOVA followed by a Bonferroni post-hoc test was used for the data analysis. Bar graphs are shown as the mean  ±  standard deviation. IB4, isolectin GS-IB4 from Griffonia simplicifolia.