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Antioxidant gene regulation by nicotinamide mononucleotide (NMN) treatment. (A,B) Quantitative analyses (n = 5 per group) demonstrated that NMN treatment (6 h) increases mRNA expression in the antioxidant genes (Nrf2 and Hmox-1) in 661W cells under 400 μM CoCl2-induced oxidative stress conditions. ## p < 0.01 and ### p < 0.001. ns, not significant. The data were analyzed using one-way ANOVA followed by a Bonferroni post-hoc test and drawn as the mean ± standard deviation.
