Table 4.
Adjusted Cox model based on CK values. The model does not allow us to conclude that for a subject alive at a determined time, if the CK is higher, the risk of death at any time thereafter increases. Age corrected for time refers to the time elapsed between onset and diagnosis.
| Adjusted Cox Model | ||||
|---|---|---|---|---|
| Predictors | Estimates | Std. Error | CI | p-Value |
| Scale(Ck) | 0.99 | 0.11 | 0.80–1.24 | 0.961 |
| Man | 1.49 | 0.30 | 1.01–2.21 | 0.046 |
| C9ORF72 | 1.15 | 0.43 | 0.56–2.37 | 0.701 |
| Age corrected for time | 1.03 | 0.01 | 1.02–1.05 | <0.001 |
| Bulbar phenotype | 1.52 | 0.32 | 1.01–2.31 | 0.047 |
| CK-phenotype interaction | 0.74 | 0.19 | 0.45–1.23 | 0.244 |
| Observations | 376 | |||
| R2 Nagelkerke | 0.083 | |||
| AIC | 1090.810 | |||