Table 1.
Group | Control | Model | Met | FG | GG |
---|---|---|---|---|---|
INS (ng/mL) | 0.96 ± 0.13 * | 2.19 ± 0.16 | 3.82 ± 0.61 ** | 2.56 ± 0.30 | 3.27 ± 0.22 * |
HOMA-IR (ng/mL × mmol/L) | 0.27 ± 0.10 * | 3.29 ± 0.60 | 2.74 ± 0.78 | 2.63 ± 0.76 | 2.64 ± 1.20 |
ADP (μg/L) | 187.52 ± 2.84 ** | 138.65 ± 2.26 | 174.46 ± 2.71 ** | 163.76 ± 1.85 ** | 163.88 ± 2.00 ** |
LEP (pg/mL) | 860.45 ± 14.48 ** | 1184.66 ± 10.96 | 935.61 ± 14.41 ** | 1006.35 ± 11.18 ** | 1031 ± 8.01 ** |
GLP-1 (pmol/L) | 5.77 ± 0.05 ** | 3.89 ± 0.07 | 5.32 ± 0.07 ** | 4.75 ± 0.05 ** | 4.95 ± 0.05 ** |
FFA (μmol/L) | 782.73 ± 14.57 ** | 1001.58 ± 10.66 | 865.76 ± 8.19 ** | 898.70 ± 9.87 ** | 886.20 ± 11.54 ** |
IL-6 (pg/mL) | 143.86 ± 2.32 ** | 194.81 ± 0.99 | 157.28 ± 2.02 ** | 169.20 ± 1.88 ** | 166.03 ± 1.42 ** |
TNF-α (ng/L) | 795.71 ± 12.63 ** | 1036.50 ± 10.05 | 885.73 ± 10.05 ** | 920.54 ± 12.49** | 904.75 ± 13.16 ** |
Liver index (%) | 0.042 ± 0.005 ** | 0.051 ± 0.004 | 0.051 ± 0.003 | 0.049 ± 0.003 | 0.046 ± 0.008 * |
Fatty tissue index (g/g) | 0.03 ± 0.005 ** | 0.10 ± 0.013 | 0.08 ± 0.014 ** | 0.09 ± 0.015 * | 0.08 ± 0.007 ** |
n = 10; * p < 0.05; ** p < 0. 01 compared with the model group). Abbreviations: INS—insulin; HOMA-IR—homeostatic model assessment of insulin resistance; ADP—adiponectin; LEP—leptin; GLP-1—glucagon-like peptide 1; FFA—free fatty acid; IL-6—interleukin-6; TNF-α—tumor necrosis factor.