Table 1.
Percentage of SIRT1 activation of thiazoles 8–11 compared with that of resveratrol (1) and compound 7.
| Compound | % SIRT1 Activation |
|---|---|
| Resveratrol (1) | 100 |
| 7 | 62.7 ± 2.7 |
| 8 | 99.1 ± 15.8 |
| 9 | 116.0 ± 25.9 |
| 10 | 73.4 ± 0.5 |
| 11 | 95.1 ± 37.1 |
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