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. 2022 Oct 5;27(19):6604. doi: 10.3390/molecules27196604

Table 3.

Comparison of bacterial loads in lungs and nasopharyngeal washes after treatment with a commercially available antibiotic and compounds 11 and 17.

Group ID
(n-value)
Bacterial Loads in Lung
(log10 CFU/mL ± SD)
Bacterial Loads in Nasopharyngeal Wash
(log10 CFU/mL ± SD)
Vehicle Control (4) 6.191 ± 0.078 5.699 ± 0.585
Ciprofloxacin * (4) 5.304 ± 0.198 * 4.648 ± 0.545 *
Compound 11 (5) 6.053 ± 0.175 5.436 ± 0.517
Compound 17 (5) 5.902 ± 0.373 5.982 ± 0.254

* Bacterial loads were significantly lower in lungs and nasopharyngeal washes of mice treated with ciprofloxacin, compared with those treated with vehicle (p ≤ 0.039).