Table 3.
Global event detection performance in the overall study population and OSA severity groups.
| Model | Metric | Group | Overall | Normal | Mild | Moderate | Severe |
|---|---|---|---|---|---|---|---|
| Binary | Sensitivity | Overall | 0.633 (3948/6239) [0.621, 0.645] |
0.583 (74/127) [0.497, 0.668] |
0.551 (252/457) [0.506, 0.597] |
0.573 (1123/1960) [0.551, 0.595] |
0.676 (2499/3695) [0.661, 0.691] |
| H | 0.539 (2384/4427) [0.524, 0.553] |
0.581 (72/124) [0.494, 0.668] |
0.529 (220/416) [0.481, 0.577] |
0.523 (894/1710) [0.499, 0.547] |
0.550 (1198/2177) [0.529, 0.571] |
||
| O/A | 0.870 (1444/1660) [0.854, 0.886] |
1.000 (2/2) [1.000, 1.000] |
1.000 (5/5) [1.000, 1.000] |
0.920 (207/225) [0.885, 0.955] |
0.861 (1230/1428) [0.843, 0.879] |
||
| C/A | 0.790 (120/152 [0.725, 0.854] |
0.000 (0/1) [0.000, 0.000] |
0.750 (27/36) [0.609, 0.892] |
0.880 (22/25) [0.753, 1.000] |
0.789 (71/90) [0.705, 0.873] |
||
| PPV | 0.695 (3948/5681) [0.683, 0.707] |
0.260 (74/285) [0.209, 0.311] |
0.475 (252/531) [0.432, 0.517] |
0.674 (1123/1666) [0.652, 0.697] |
0.781 (2499/3199) [0.767, 0.796] |
||
| FP/patient | Overall | 39.0 [30.5, 47.6] |
23.4 [18.4, 28.5] |
39.9 [35.4, 44.3] |
36.1 [32.3, 40.0] |
52.8 [39.1, 66.4] |
|
| In-sleep | 26.0 [18.6, 33.4] |
17.2 [13.1, 21.4] |
28.0 [23.7, 32.3] |
25.9 [22.2, 29.5] |
31.0 [18.7, 43.4] |
||
| Multiclass | Sensitivity | Overall | 0.622 (3883/6239) [0.610, 0.634] |
0.543 (69/127) [0.457, 0.630] |
0.490 (224/457) [0.444, 0.536] |
0.557 (1092/1960) [0.535, 0.579] |
0.676 (2498/3695) [0.661, 0.691] |
| H | 0.525 (2323/4427) [0.510, 0.539] |
0.540 (67/124) [0.453, 0.628] |
0.476 (198/416) [0.428, 0.524] |
0.508 (868/1710) [0.484, 0.531] |
0.547 (1190/2177) [0.526, 0.568] |
||
| O/A | 0.869 (1443/1660) [0.853, 0.886] |
0.500 (1/2) [0.000, 1.000] |
1.000 (5/5) [1.000, 1.000] |
0.898 (202/225) [0.858, 0.937] |
0.865 (1235/1428) [0.847, 0.883] |
||
| C/A | 0.770 (117/152) [0.703, 0.837] |
1.000 (1/1) [1.000, 1.000] |
0.583 (21/36) [0.422, 0.744] |
0.880 (22/25) [0.753, 1.000] |
0.811 (73/90) [0.730, 0.892] |
||
| PPV | 0.695 (3883/5585) [0.683, 0.707] |
0.199 (69/347) [0.157, 0.241] |
0.489 (224/458) [0.443, 0.535] |
0.673 (1092/1622) [0.650, 0.696] |
0.791 (2498/3158) [0.777, 0.805] |
||
| FP/patient | Overall | 38.5 [29.9, 47.0] |
30.9 [23.7, 38.1] |
33.4 [29.3, 37.5] |
35.3 [30.3, 40.2] |
50.1 [37.0, 63.2] |
|
| In-sleep | 25.3 [17.7, 32.8] |
22.2 [16.2, 28.3] |
24.1 [20.4, 27.9] |
24.7 [20.0, 29.3] |
28.7 [16.6, 40.8] |
Data are presented as value (numerator/denominator, if applicable) [95% confidence intervals]. PPV, positive predictive value; FP, false-positive detection; H, hypopnea; O/A, obstructive apnea; C/A, central apnea.