Table 4.
Effects of cholelithiasis diagnosis on ceramide concentrations after adjusting for age, obesity, sex and levels of TG and TC (generalized multivariable linear model).
| Dependent Variables | Model Coefficient (β) | p |
|---|---|---|
| Sph | 0.001 | NS |
| SPA | −0.373 | <0.0001 |
| C14:0-Cer | −1.014 | <0.0001 |
| C16:0-Cer | −52.120 | <0.0001 |
| C18:1-Cer | 0.045 | NS |
| C18:0-Cer | −2.545 | NS |
| C20:0-Cer | 19.839 | <0.0001 |
| C22:0-Cer | 17.868 | NS |
| C24:1-Cer | 83.609 | <0.0001 |
| C24:0-Cer | 55.559 | NS |
| C16:0-LacCer | 177.932 | 0.01 |
| C18:0-LacCer | −7.504 | NS |
| C18:1-LacCer | 8.419 | <0.0001 |
| C24:1-LacCer | −252.245 | <0.0001 |
| C24:0-LacCer | −84.788 | <0.0001 |
Sph—sphingosine, SPA—sfinganine; Cer—ceramide, LacCer—lactosylceramide, TG—triglicerides, TC—total cholesterol, NS—not significant.