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. 2022 Sep 26;27(19):6361. doi: 10.3390/molecules27196361

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The evaluation of chronic wound healing on the aged mouse. (A) Full-thickness skin wound of bFGF-Gel group, (B) bFGF-Gel dressing covered on the wound, (C) Full-thickness skin wound of bFGF-Sol group, (D) bFGF was spraying on the wound, (E) Digital photos of wounds on the dorsum of mice after treatment by using no treatment (Blank), spraying bFGF-Sol and bFGF-Gel hydrogel dressings on different days after the surgery. (F) Summary graph of the wound closure rate of these three groups. The data were represented as mean ± SD (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001. Scale bar =10 mm.