Table 1.
Gene list of “FoxO3”.
| Gene Symbol | Gene Name | Log Ratio (Dex vs. Con) |
|---|---|---|
| LCN2 | Lipocalin 2 | 7.43 |
| CDKN1A | Cyclin Dependent Kinase Inhibitor 1A | 2.134 |
| FOS | Fos Proto-Oncogene, AP-1 Transcription Factor Subunit | 1.912 |
| GADD45B | Growth Arrest And DNA Damage Inducible Beta | 1.682 |
| Mt1 | Metallothionein-1 | 1.535 |
| Mt2 | Metallothionein-2 | 1.291 |
| TPX2 | TPX2 Microtubule Nucleation Factor | 1.242 |
| IRS2 | Insulin Receptor Substrate 2 | 1.079 |
| FASN | Fatty Acid Synthase | 1.076 |
| PPP1R15A | Protein Phosphatase 1 Regulatory Subunit 15A | 1.049 |
| EGR1 | Early Growth Response 1 | 0.982 |
| UBC | Ubiquitin C | 0.974 |
| FBXO32 | F-Box Protein 32 | 0.906 |
| MTHFD2 | Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2 | 0.902 |
| GABRR2 | Gamma-Aminobutyric Acid Type A Receptor Subunit Rho2 | 0.837 |
| EIF4EBP1 | Eukaryotic Translation Initiation Factor 4E Binding Protein 1 | 0.79 |
| JUNB | JunB Proto-Oncogene, AP-1 Transcription Factor Subunit | 0.738 |
| BCL2L11 | BCL2-Like 11 | 0.733 |
| OPTN | Optineurin | 0.677 |
| CDKN1B | Cyclin Dependent Kinase Inhibitor 1B | 0.668 |
| MAP1LC3A | Microtubule Associated Protein 1 Light Chain 3 Alpha | 0.633 |
| PAK1 | P21 (RAC1) Activated Kinase 1 | −0.664 |
| PTEN | Phosphatase And Tensin Homolog | −0.676 |
| CCNE2 | Cyclin E2 | −0.726 |
| GRB14 | Growth Factor Receptor Bound Protein 14 | −0.772 |
| VCAM1 | Vascular Cell Adhesion Molecule 1 | −0.784 |
| FMOD | Fibromodulin | −0.799 |
| IGF1 | Insulin-Like Growth Factor 1 | −0.799 |
| CCND1 | Cyclin D1 | −0.816 |
| FN1 | Fibronectin 1 | −1.075 |
| NFKBIA | NFKB Inhibitor Alpha | −1.296 |
| TCIM | Transcriptional And Immune Response Regulator | −1.31 |
| DDIT4 | DNA Damage Inducible Transcript 4 | −4.14 |
In upstream analysis using IPA software, the “FoxO3” category was listed in the comparison between the control and DEX groups. The activation Z score of this category was 2.795.