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. 2022 Oct 9;15(19):7003. doi: 10.3390/ma15197003

Table 3.

Kinetic parameters of irinotecan release from ulvan-silica nanoplatforms.

Irinotecan Loaded Ulvan-Silica Nanoplatforms Three-Parameter Model Maximum Amount of Drug Released (%)
ΔG
(1021 J)
kd
(min−1)
koff
(min−1)
kon
(min−1)
R 2
Iri@Ulv@SBA-NH2 −3.36 0.032 0.015 0.034 0.9978 96.1 ± 3.9
Iri@Ulv@MCMB-NH2 1.87 0.019 1.501 0.969 0.9976 97.4 ± 2.6