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Experimental autoimmune myocarditis murine model. In the EAM model, cardiac myosin or the relevant peptide in Freund’s complete adjuvant is injected subcutaneously into mice on day 0 and day 7. The immune response, the histological changes, and the genetic susceptibility observed in EAM are similar to giant cell myocarditis. #: The numbers are identifying the epitope of myosin heavy chain (MYHC) used for the induction of myocarditis.
