TABLE 2.

Serum antibody reactivity to two different VacA antigens

Patient classification	No. of patients	ELISA values by antibody class and type of VacA antigena
		IgG			IgA
		H. pylori sonicate	s1/m1	s2/m2	s1/m1	s2/m2
H. pylori negative	19	0.41 ± 0.05	0.07 ± 0.02	0.16 ± 0.05	0.04 ± 0.01	0.05 ± 0.01
H. pylori positive	39	6.02 ± 0.30	0.37 ± 0.04c	0.33 ± 0.04b	0.39 ± 0.03c	0.11 ± 0.02
s1/m1	19	5.54 ± 0.46	0.56 ± 0.09e	0.25 ± 0.04d	0.56 ± 0.08e	0.07 ± 0.01
s1/m2	12	6.17 ± 0.56	0.20 ± 0.04	0.42 ± 0.07	0.26 ± 0.08	0.15 ± 0.08
s2/m2	8	6.90 ± 0.49	0.18 ± 0.07	0.38 ± 0.09	0.17 ± 0.08	0.14 ± 0.08

^aValues for ELISA reactivity of sera with H. pylori sonicate are reported as OD ratios. All other values are ODs. 

^bP = 0.007 compared with values obtained for the H. pylori-negative group. 

^cP < 0.0005 compared with values obtained for the H. pylori-negative group. 

^dP = 0.03 compared with values obtained for the other two groups of H. pylori-positive patients. 

^eP < 0.01 compared with values obtained for each of the three other groups (H. pylori negative, s2/m2, s1/m2).