TABLE 2.
Patient classification | No. of patients | ELISA
values by antibody class and type of VacA
antigena
|
||||
---|---|---|---|---|---|---|
IgG
|
IgA
|
|||||
H. pylori sonicate | s1/m1 | s2/m2 | s1/m1 | s2/m2 | ||
H. pylori negative | 19 | 0.41 ± 0.05 | 0.07 ± 0.02 | 0.16 ± 0.05 | 0.04 ± 0.01 | 0.05 ± 0.01 |
H. pylori positive | 39 | 6.02 ± 0.30 | 0.37 ± 0.04c | 0.33 ± 0.04b | 0.39 ± 0.03c | 0.11 ± 0.02 |
s1/m1 | 19 | 5.54 ± 0.46 | 0.56 ± 0.09e | 0.25 ± 0.04d | 0.56 ± 0.08e | 0.07 ± 0.01 |
s1/m2 | 12 | 6.17 ± 0.56 | 0.20 ± 0.04 | 0.42 ± 0.07 | 0.26 ± 0.08 | 0.15 ± 0.08 |
s2/m2 | 8 | 6.90 ± 0.49 | 0.18 ± 0.07 | 0.38 ± 0.09 | 0.17 ± 0.08 | 0.14 ± 0.08 |
Values for ELISA reactivity of sera with H. pylori sonicate are reported as OD ratios. All other values are ODs.
P = 0.007 compared with values obtained for the H. pylori-negative group.
P < 0.0005 compared with values obtained for the H. pylori-negative group.
P = 0.03 compared with values obtained for the other two groups of H. pylori-positive patients.
P < 0.01 compared with values obtained for each of the three other groups (H. pylori negative, s2/m2, s1/m2).