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. 2022 Sep 24;11(19):5632. doi: 10.3390/jcm11195632

Table A3.

Method Information of the SEQDESIGN Procedure.

Method Information
Boundary Method Alpha Beta Unified Family Alternative
Reference
Drift
Rho Tau C
Lower Beta O’Brien-Fleming . 0.20000 0.5 0 0.94812 −0.08 −2.8825
Lower Alpha O’Brien-Fleming 0.02500 . 0.5 0 1.93438 −0.08 −2.8825
Boundary Information (Standardized Z Scale)
Null Reference = 0
_Stage_ Alternative Boundary Values
Information Level Reference Lower
Proportion Actual N Lower Alpha Beta
1 0.5000 649.1273 208.4997 −2.03824 −2.73563 −0.69739
2 1.0000 1298.255 416.9994 −2.88250 −1.93438 −1.93438