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. 2022 Oct 15;17:454. doi: 10.1186/s13018-022-03348-2

Table 2.

Tabulation of different ROI CT attenuation values, expressed in Hounsfield unit (HU) for L1 to L4 and their mean values and 95% confidence interval (CI), for DXA-defined normal, osteopenia, and osteoporosis subgroup

Vertebrae Methods Normal Osteopenia Osteoporosis p
L1 BMD (g/cm2) 1.11 (1.02, 1.19)* 0.89 (0.84, 0.96) 0.71 (0.62, 0.77)▲,* < 0.001
Round ROICT (HU) 164.00 (131.00, 223.00)* 131.00 (75.25, 165.75) 73.00 (33.00, 91.00)▲,* < 0.001
Oval ROICT (HU) 172.00 (128.50, 219.00)* 128.00 (85.00, 165.00) 69.00 (36.00, 93.00)▲,* < 0.001
Right ROICT (HU) 163.00 (117.50, 196.00)* 116.50 (89.75, 148.25) 74.00 (50.00, 96.00)▲,* < 0.001
Front ROICT (HU) 169.00 (134.00, 219.50)* 135.00 (83.00, 168.25) 71.00 (38.00, 92.00)▲,* < 0.001
Left ROICT (HU) 189.00 (138.00, 203.00)* 130.00 (101.00, 163.50) 73.00 (47.00, 98.00)▲,* < 0.001
L2 BMD (g/cm2) 1.18 (1.07, 1.27)* 0.94 (0.90, 0.98) 0.75 (0.63, 0.83)▲,* < 0.001
Round ROICT (HU) 163.00 (141.00, 213.00)* 106.00 (74.75, 139.25) 68.00 (38.00, 99.00)▲,* < 0.001
Oval ROICT (HU) 156.00 (127.00, 208.00)* 110.00 (73.50, 141.25) 73.00 (36.00, 106.00)▲,* < 0.001
Right ROICT (HU) 140.00 (109.50, 200.00)* 103.50 (91.25, 137.75) 71.00 (41.00, 102.00)▲,* < 0.001
Front ROICT (HU) 153.00 (127.50, 213.00)* 110.50 (80.00, 146.75) 69.00 (40.00, 104.00)▲,* < 0.001
Left ROICT (HU) 162.00 (126.00, 200.50)* 115.50 (84.25, 152.75) 71.00 (31.00, 105.00)▲,* < 0.001
L3 BMD (g/cm2) 1.29 (1.15, 1.38)* 1.03 (0.95, 1.07) 0.80 (0.65, 0.86)▲,* < 0.001
Round ROICT (HU) 153.00 (111.50, 208.00)* 95.50 (61.00, 132.00) 53.00 (27.00, 75.00)▲,* < 0.001
Oval ROICT (HU) 152.00 (116.00, 205.00)* 94.00 (62.50, 138.50) 48.00 (28.00, 75.00)▲,* < 0.001
Right ROICT (HU) 154.00 (110.50, 199.00)* 100.50 (75.87, 118.50) 68.00 (36.00, 92.00)▲,* < 0.001
Front ROICT (HU) 152.00 (119.00, 210.00)* 95.00 (64.50, 135, 75) 54.00 (24.00, 79.00)▲,* < 0.001
Left ROICT (HU) 166.00 (134.00, 205.00)* 100.50 (78.50, 127.50) 58.00 (37.00, 91.00)▲,* < 0.001
L4 BMD (g/cm2) 1.29 (1.15, 1.38)* 1.02 (0.95, 1.07) 0.82 (0.68, 0.88)▲,* < 0.001
Round ROICT (HU) 166.00 (118.00, 218.50)* 99.00 (60.50, 132.00) 58.00 (16.00, 81.00)▲,* < 0.001
Oval ROICT (HU) 164.00 (115.50, 206.50)* 94.00 (61.25, 130.50) 55.00 (23.00, 85.00)▲,* < 0.001
Right ROICT (HU) 179.00 (134.00, 247.00)* 134.00 (97.50, 173.25) 81.00 (46.00, 103.00)▲,* < 0.001
Front ROICT (HU) 171.00 (121.00, 222.00)* 101.50 (69.00, 135.25) 65.00 (22.00, 88.00)▲,* < 0.001
Left ROICT (HU) 196.00 (128.00, 226.50)* 119.00 (93.50, 152.50) 83.00 (53.00, 104.00)▲,* < 0.001
L1–L4 BMD (g/cm2) 1.24 (1.10, 1.28)* 0.99 (0.92, 1.03) 0.77 (0.64, 0.84)▲,* < 0.001
Round ROICT (HU) 162.25 (123.25, 217.25)* 107.00 (68.88, 142.00) 53.00 (35.00, 85.25)▲,* < 0.001
Oval ROICT (HU) 158.75 (123.38, 213.13)* 102.63 (71.69, 140.81) 54.75 (32.25, 88.50)▲,* < 0.001
Right ROICT (HU) 156.75 (120.88, 206.88)* 111.50 (93.94, 149.13) 74.00 (47.25, 98.00)▲,* < 0.001
Front ROICT (HU) 159.00 (125.13, 214.75)* 107.25 (70.94, 144.75) 57.25 (53.50, 85.75)▲,* < 0.001
Left ROICT (HU) 171.25 (135.75, 214.50)* 115.00 (96.63, 142.50) 68.00 (41.75, 103.75)▲,* < 0.001

Indicates a statistically significant difference compared to the normal

*Indicates a statistically significant difference compared to osteopenia