Table 1.

Trabecular bone parameters in the distal femur of 12-week WT and KO mice

	WT	KO	p value
Parameters of µCT
BV/TV (%)	6.967 ± 0.256	1.287 ± 0.220	< 0.0001
Tb. Th(mm)	0.043 ± 0.003	0.037 ± 0.001	0.0441
Tb. N(mm−1)	1.651 ± 0.078	0.372 ± 0.020	< 0.0001
Tb. Sp(mm)	0.255 ± 0.009	0.449 ± 0.042	0.0014
Connectivity	231.333 ± 11.060	104.000 ± 14.422	0.0003
Tb. Pf(mm−1)	33.477 ± 0.950	60.404 ± 2.033	< 0.0001
SMI	2.259 ± 0.111	2.703 ± 0.123	0.0096

Parameters were expressed as mean ± standard deviation, and comparisons between the two groups were performed using the Student’s t test

p value with statistical significance was labeled in bold