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Mon attenuates the bone loss and decreases the number of osteoclasts in bone tissue of LPS-treated mice as evidenced by (A) HE and (B(a)) TRAP staining of the femora (n = 8). (B(b)) The quantifications of number of osteoclasts on the bone surface (Oc.N/BS) were calculated based on TRAP staining by using the Image J software. The data are expressed as means ± SD. ## p < 0.01 compared with Sham group; * p < 0.05, ** p < 0.01 compared with LPS group.
