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. 2022 Sep 25;27(19):6316. doi: 10.3390/molecules27196316

Table 3.

Clinical Trials Involving Pterostilbene.

Clinical Trial Subjects The Drug Used/Diet Status Findings Reference
Studying the Effects of ElevATP on Body Composition and Athletic Performance of Healthy Individuals Healthy 18–35-year-old males ElevATP with and without caffeine and Vitamins Completed Improved strength and power output in the lower body ClinicalTrials.gov Identifier: NCT02819219
Study of Pharmacokinetics and Safety of Basis™ in Subjects with Acute Kidney Injury Patients with Acute Kidney Injury Basis Completed Nicotinamide riboside with pterostilbene increased whole-blood NAD + levels ClinicalTrials.gov Identifier: NCT03176628
Effect of PTS on Cholesterol and Hypertension Patients with hyperlipidemia and increased
Blood Pressure
1. PTS (low dosage of 50 mg and high dosage of 125 mg)
2. Low dose combination of PTS and grape extract (50 mg + 100 mg)
Completed PTS increased LDL and reduced blood pressure in adults [95] ClinicalTrials.gov Identifier: NCT01267227
Evaluating Safety and Benefits of Basis™ Among Elderly Subjects 60–80-year-old healthy subjects Basis™ Completed Yet to be published ClinicalTrials.gov Identifier: NCT02678611
A Trial of Nicotinamide/PTS Supplement in Amyotrophic Lateral Sclerosis Patients with Amyotrophic Lateral Sclerosis EH301 (nicotinamide riboside/PTS) Recruiting Yet to be published ClinicalTrials.gov Identifier: NCT05095571
Effect of Blueberries in Postmenopausal Women with Elevated Blood Pressure for Improving Vascular Endothelial Function Postmenopausal women with elevated blood pressure, hypertension, and endothelial dysfunction Blueberry powder Active
Phase 2
Phase 3
Yet to be published ClinicalTrials.gov Identifier: NCT03370991
Supplementing Wild Blueberries to Study Cardiovascular Health in Middle-aged/Older Men 45- to 70-year-old men with hypertension and endothelial dysfunction Blueberry powder Recruiting
Phase 1
Phase 2
Yet to be published ClinicalTrials.gov Identifier: NCT04530916
Effect of High-intensity Training and Daily Consumption of Basis™ on Muscle Metabolism and Exercise 18- to 25-year-old healthy men NRPT
(125 mg nicotinamide riboside and 25 mg PTS)
Phase 1 Yet to be published ClinicalTrials.gov Identifier: NCT04050358
Study of Treating Megestrol Acetate with or without PTS in Patients with Endometrial Cancer Undergoing Hysterectomy Women with Atypical Endometrial Hyperplasia and
Endometrial Carcinoma
Megestrol Acetate with or without PTS Recruiting
Phase 2
Yet to be published ClinicalTrials.gov Identifier: NCT03671811
Protection of Basis™ in Acute Kidney Injury Patients with Acute Kidney Injury Nicotinamide riboside + PTS Recruiting
Phase 2
Yet to be published ClinicalTrials.gov Identifier: NCT04342975
Studying the Benefit of Supplementation with Short-term Curcumin and Multi-polyphenol Non-smokers in good health not taking medications or dietary supplements Polyresveratrol supplementation
(100 mg of trans-PTS, 100 mg of curcumin phytosome, 100 mg of quercetin phytosome, 100 mg of green tea phytosome, and 100 mg of trans-resveratrol)
Unknown Not Published ClinicalTrials.gov Identifier: NCT02998918
Studying effects of Nicotinamide Riboside and PTS on Muscle Regeneration in Elderly Humans 55- to 80-year- old individuals Nicotinamide riboside/PTS-NRPT (500 mg/100 mg twice daily) Completed Not published ClinicalTrials.gov Identifier: NCT03754842
Evaluating Sirtuin Supplements to Benefit Elderly Trauma Patients to study recovery of function Individuals 65 years and older presenting to trauma bay Nicotinamide riboside and PTS Unknown Not published ClinicalTrials.gov Identifier: NCT03635411
Effects of a Seven-day BASIS™ Supplementation on Menopausal Syndrome, Estradiol levels and Measurements of the Urinary Vitamin B3 Women 35 years or older BASIS™ Completed Not published ClinicalTrials.gov Identifier: NCT04841499