Table 3.
Clinical Trials Involving Pterostilbene.
Clinical Trial | Subjects | The Drug Used/Diet | Status | Findings | Reference |
---|---|---|---|---|---|
Studying the Effects of ElevATP on Body Composition and Athletic Performance of Healthy Individuals | Healthy 18–35-year-old males | ElevATP with and without caffeine and Vitamins | Completed | Improved strength and power output in the lower body | ClinicalTrials.gov Identifier: NCT02819219 |
Study of Pharmacokinetics and Safety of Basis™ in Subjects with Acute Kidney Injury | Patients with Acute Kidney Injury | Basis | Completed | Nicotinamide riboside with pterostilbene increased whole-blood NAD + levels | ClinicalTrials.gov Identifier: NCT03176628 |
Effect of PTS on Cholesterol and Hypertension | Patients with hyperlipidemia and increased Blood Pressure |
1. PTS (low dosage of 50 mg and high dosage of 125 mg) 2. Low dose combination of PTS and grape extract (50 mg + 100 mg) |
Completed | PTS increased LDL and reduced blood pressure in adults [95] | ClinicalTrials.gov Identifier: NCT01267227 |
Evaluating Safety and Benefits of Basis™ Among Elderly Subjects | 60–80-year-old healthy subjects | Basis™ | Completed | Yet to be published | ClinicalTrials.gov Identifier: NCT02678611 |
A Trial of Nicotinamide/PTS Supplement in Amyotrophic Lateral Sclerosis | Patients with Amyotrophic Lateral Sclerosis | EH301 (nicotinamide riboside/PTS) | Recruiting | Yet to be published | ClinicalTrials.gov Identifier: NCT05095571 |
Effect of Blueberries in Postmenopausal Women with Elevated Blood Pressure for Improving Vascular Endothelial Function | Postmenopausal women with elevated blood pressure, hypertension, and endothelial dysfunction | Blueberry powder | Active Phase 2 Phase 3 |
Yet to be published | ClinicalTrials.gov Identifier: NCT03370991 |
Supplementing Wild Blueberries to Study Cardiovascular Health in Middle-aged/Older Men | 45- to 70-year-old men with hypertension and endothelial dysfunction | Blueberry powder | Recruiting Phase 1 Phase 2 |
Yet to be published | ClinicalTrials.gov Identifier: NCT04530916 |
Effect of High-intensity Training and Daily Consumption of Basis™ on Muscle Metabolism and Exercise | 18- to 25-year-old healthy men | NRPT (125 mg nicotinamide riboside and 25 mg PTS) |
Phase 1 | Yet to be published | ClinicalTrials.gov Identifier: NCT04050358 |
Study of Treating Megestrol Acetate with or without PTS in Patients with Endometrial Cancer Undergoing Hysterectomy | Women with Atypical Endometrial Hyperplasia and Endometrial Carcinoma |
Megestrol Acetate with or without PTS | Recruiting Phase 2 |
Yet to be published | ClinicalTrials.gov Identifier: NCT03671811 |
Protection of Basis™ in Acute Kidney Injury | Patients with Acute Kidney Injury | Nicotinamide riboside + PTS | Recruiting Phase 2 |
Yet to be published | ClinicalTrials.gov Identifier: NCT04342975 |
Studying the Benefit of Supplementation with Short-term Curcumin and Multi-polyphenol | Non-smokers in good health not taking medications or dietary supplements | Polyresveratrol supplementation (100 mg of trans-PTS, 100 mg of curcumin phytosome, 100 mg of quercetin phytosome, 100 mg of green tea phytosome, and 100 mg of trans-resveratrol) |
Unknown | Not Published | ClinicalTrials.gov Identifier: NCT02998918 |
Studying effects of Nicotinamide Riboside and PTS on Muscle Regeneration in Elderly Humans | 55- to 80-year- old individuals | Nicotinamide riboside/PTS-NRPT (500 mg/100 mg twice daily) | Completed | Not published | ClinicalTrials.gov Identifier: NCT03754842 |
Evaluating Sirtuin Supplements to Benefit Elderly Trauma Patients to study recovery of function | Individuals 65 years and older presenting to trauma bay | Nicotinamide riboside and PTS | Unknown | Not published | ClinicalTrials.gov Identifier: NCT03635411 |
Effects of a Seven-day BASIS™ Supplementation on Menopausal Syndrome, Estradiol levels and Measurements of the Urinary Vitamin B3 | Women 35 years or older | BASIS™ | Completed | Not published | ClinicalTrials.gov Identifier: NCT04841499 |