Table 1.
Patient characteristics (n = 394).
| Characteristic | POD (n = 99) 25.10% |
Non POD (n = 295) 74.90% |
p |
|---|---|---|---|
| n = 394 | |||
| Age (years) | 74 [71;77] | 72 [68;76] | 0.004 a |
| Sex | |||
| Female | 51 (41.5%) | 145 (49.2%) | 0.684 b |
| ASA PS | <0.001 b | ||
| 1–2 | 43 (43.4%) | 203 (68.8%) | |
| 3–4 | 56 (56.6%) | 92 (31.2%) | |
| Charlson Comorbidity Index | 2.14 ±1.5 c | 1.43 ± 1.6 c | <0.001 a |
| Frailty status | <0.001 b | ||
| Pre-frail | 50 (51.0%) | 143 (49.1%) | |
| frail | 30 (30.6%) | 30 (10.3%) | |
| Site of surgery | <0.001 b | ||
| intracranial | 2 (2.0%) | 7 (2.4%) | |
| intrathoracic, intra-abdominal or pelvic | 67 (67.7%) | 122 (41.4%) | |
| peripheral | 30 (30.3%) | 166 (56.3%) | |
| Duration of Anaesthesia (min) | 360 [220;495] | 157 [100;260] | <0.001 b |
Data are expressed as medians [25th quartile; 75th quartile] except for categorical data, which are expressed as frequencies (percentages). p-values are with respect to Mann–Whitney U test (a) or Chi-squared test (b) between patients with or without POD. Additionally, data for Charlson Comorbidity Index are presented as means ± SD (c). p ≤ 0.05 was considered as statistically significant. SD—standard deviation, POD—postoperative delirium, ASA PS—physical status according to the American Society of Anesthesiologists, min—minutes.