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. 2022 Sep 26;27(19):6360. doi: 10.3390/molecules27196360

Table 6.

α-Glucosidase and α-amylase inhibitions of Cydonia oblonga of methanolic extract and subsequent purified fractions at different concentrations.

Sample Concentration
(µg/mL)
% α-Glucosidase Inhibition IC50
(µg/mL)
% α-Amylase Inhibition IC50
(µg/mL)
Mean ± SEM Mean ± SEM
Met-Ext 1000 78.21 ± 0.67 57 77.98 ± 0.57 52
500 73.51 ± 0.56 76.29 ± 0.36
250 64.79 ± 0.14 74.32 ± 0.25
125 60.28 ± 0.38 68.38 ± 0.68
62.5 52.51 ± 1.06 57.28 ± 0.52
F1 1000 55.01 ± 0.29 500 79.72 ± 0.02 57
500 50.97 ± 0.39 78.22 ± 0.72
250 43.13 ± 0.34 74.02 ± 0.76
125 47.24 ± 0.29 67.97 ± 0.80
62.5 32.41 ± 0.74 52.58 ± 0.10
F 2 1000 56.10 ± 0.24 494 79.97 ± 0.30 45
500 51.88 ± 0.38 79.27 ± 0.28
250 47.62 ± 0.91 76.22 ± 0.62
125 47.09 ± 0.01 75.82 ± 0.56
62.5 30.89 ± 1.99 70.18 ± 0.48
F3 1000 62.44 ± 1.02 200 82.16 ± 0.48 49
500 57.61 ± 0.28 80.41 ± 0.92
250 55.88 ± 0.18 78.06 ± 0.65
125 48.19 ± 0.15 76.72 ± 0.53
62.5 43.27 ± 1.02 74.67 ± 0.59
F4 1000 70.52 ± 0.15 370 77.37 ± 0.28 54
500 63.86 ± 0.03 76.57 ± 0.04
250 55.04 ± 0.08 74.47 ± 0.92
125 49.04 ± 0.71 68.88 ± 0.38
62.5 43.25 ± 0.90 57.18 ± 0.05
F5 1000 62.18 ± 0.92 180 72.14 ± 0.30 220
500 59.92 ± 0.49 61.50 ± 0.58
250 52.92 ± 0.32 53.44 ± 0.28
125 48.84 ± 0.73 46.16 ± 0.74
62.5 36.73 ± 0.07 38.58 ± 0.48
F6 1000 72.68 ± 0.22 125 74.24 ± 0.29 59
500 68.05 ± 0.52 67.38 ± 1.62
250 57.39 ± 0.99 62.67 ± 0.25
125 50.92 ± 0.27 56.52 ± 0.49
62.5 46.35 ± 0.89 51.81 ± 0.76
F7 1000 57.33 ± 0.05 495 56.58 ± 0.10 500
500 51.61 ± 0.12 50.42 ± 0.46
250 46.84 ± 0.83 44.39 ± 0.78
125 39.60 ± 0.39 38.28 ± 0.60
62.5 34.68 ± 0.06 31.09 ± 1.05
Acarbose 1000 87.65 ± 0.71 30 85.99 ± 0.44 32
500 83.05 ± 0.65 83.61 ± 0.58
250 78.90 ± 1.02 76.85 ± 0.96
125 71.83 ± 0.99 70.47 ± 0.78
62.5 65.15 ± 0.75 64.89 ± 0.71