TABLE 1.
Levels of anti-6B antibodies before and after vaccination
| Serum donor | Total IgG anti-6B
Aba (mg/liter)
|
6B-specific IgG
Aba (mg/liter)
|
Polyspecific
Abb (mg/liter)
|
|||
|---|---|---|---|---|---|---|
| Preimmune | Postimmune | Preimmune | Postimmune | Preimmune | Postimmune | |
| P3 | 2 | 6 | 0.7 | 2 | 1.3 | 4 |
| P4 | 6.6 | 7.2 | 2.5 | 3.2 | 4.1 | 4 |
| P11 | 16.3 | 47.9 | 3.3 | 22.2 | 13 | 25.7 |
| P23 | 1.9 | 15.5 | 1 | 10.9 | 0.9 | 4.6 |
| P24 | 1.4 | 7.5 | 1 | 8.4 | 0.4 | −0.9 |
| P26 | 5.8 | 20.9 | 5.7 | 24.2 | 0.1 | −3.3 |
a
Total IgG anti-6B antibody (Ab) was measured by ELISA as described in Materials and Methods. 6B-specific IgG antibody was measured by ELISA, but 9V PS was present in the buffer.
b
The values were obtained by subtracting 6B-specific antibody (Ab) concentration from total antibody concentration. When the polyspecific antibody is much less than the 6B-specific antibody, the polyspecific antibody concentration can become artifactually negative.