Table 1.
Demographic and laboratory results of patients and control group.
| Demographic Characteristics | Patients Group No = 124 |
Control Group No = 121 |
p-Value |
|---|---|---|---|
| Mean ± SD/Median | Mean ± SD/Median | ||
| Age (years) | 48.55 ± 10.45 | 48.37 ± 8.92 | 0.887 b |
| Sex Female (n, %) Male (n, %) |
121 (97.6%) | 119 (98.3%) | 0.671 c |
| 3 (2.4%) | 2 (1.7%) | ||
| Laboratory findings Cell counts | |||
| Erythrocytes (×106/µL) | 4.22 ± 0.38 | 4.44 ± 0.38 | 0.001 a |
| Leucocytes (109/µL) | 5.1 ± 1.71 | 6.94 ± 2.17 | 0.001 a |
| Neutrophils (109/µL) | 3.11 ± 0.67 | 4.27 ± 1.96 | 0.001 a |
| Lymphocytes (109/µL) | 1.12 ± 0.09 | 1.97 ± 1.21 | 0.001 a |
| Monocyte (109/µL) | 0.33 ± 0.14 | 0.64 ± 0.16 | 0.001 a |
| Platelets (109/L) | 25.8 ± 51.4 | 29.6 ± 68.18 | 0.001 a |
| RDW-CV (%) | 12.97 ± 1.16 | 13.13 ± 0.84 | 0.086 a |
| Cellular ratios | |||
| MPVPCTR | 39.33 ± 10.93 | 42.22 ± 25.36 | 0.246 b |
| PDWPCTR | 46.46 ± 12.7 | 49.76 ± 29.45 | 0.255 b |
| MLR | 0.29 ± 0.12 | 0.1 ± 0.52 | 0.001 a |
| NLR | 2.8 ± 0.71 | 2.2 ± 0.96 | 0.001 a |
| PLR | 233.75 ± 56.34 | 153.7 ± 60.8 | 0.001 a |
| Immunological results | |||
| RF (U/mL) | 52.18 ± 61 | 9.32 ± 18.55 | 0.001 a |
| IgA (mg/dL) | 293.67 ± 15.98 | 222.9 ± 93.9 | 0.001 a |
| IgG (mg/dL) | 1656.94 ± 708.73 | 1200.5 ± 315.2 | 0.001 a |
| IgM (mg/dL) | 168.4 ± 121.31 | 116.84 ± 45.75 | 0.001 a |
| Gammaglobulins (g/dL) | 1.45 ± 0.4 | 1.05 ± 0.16 | 0.001 a |
| C3 (mg/dL) | 133.48 ± 116.22 | 131.33 ± 16.27 | 0.003 a |
| C4 (mg/dL) | 22.02 ± 10.33 | 32.32 ± 10.7 | 0.001 a |
| ANA Positive (n, %) Negative (n, %) |
105 (84.67%) | - | - |
| 19 (15.32%) | - | - | |
| Anti-Ro/SSA Positive (n, %) Negative (n, %) |
105 (84.67%) | - | - |
| 19 (15.32%) | - | - | |
| Anti-La/SSB Positive (n, %) Negative (n, %) |
76 (61.29%) | - | - |
| 48 (38.70%) | - | - | |
| Inflammatory results | |||
| hs-CRP (mg/L) | 24.22 ± 25.53 | 5.75 ± 4.74 | 0.001 a |
| Clinical scores | |||
| ESSDAI score | 16.96 ± 7.8 | - | - |
| ESSDAI score 5–13 | 50 (40.32%) | - | - |
| ESSDAI score ≥14 | 74 (59.67%) | - | - |
| VAS pain score (mm) | 18.87 ± 26.9 | - | - |
Abbreviations: RDW-CV, red cell distribution width-coefficient of variation; MPVPCTR, mean platelet volume to Plateletcrit ratio; PDWPCTR, platelet distribution width to platelet crit ratio; MLR, monocyte to lymphocyte ratio; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; RF, rheumatoid factor; C3 and C4, complement 3 and 4; hs-CRP, high sensitivity C-reactive protein; ANA, antinuclear antibodies; SD, standard deviation; VAS, visual analogue scale; ESSDAI, EULAR Sjögren’s Syndrome Disease Activity Index. a Mann–Whitney U test, b Independent samples t-test, c Pearson Chi-Square; statistical significance < 0.05.