Table 1.

Mean ± standard deviation of volume and percentage of structures into defect obtained by 3D-morphometry on micro-CT images.

Parameter	Period (Days)	Groups
		BC	BCP	BT	BTP
Total volume (TV, mm3)	14	36.52 ± 3.59 aA	36.22 ± 3.48 aA	114.0 ± 9.20 bA	112.8 ± 11.84 bA
	42	36.60 ± 3.35 aA	35.80 ± 4.38 aA	115.4 ± 13.3 bA	106.7 ± 13.72 bA
Material volume (MV, mm3)	14	-	-	41.09 ± 5.90 aA	42.35 ± 8.32 aA
	42	-	-	41.28 ± 7.73 aA	35.97 ± 5.57 aA
Bone volume (BV, mm3)	14	2.93 ± 1.43 aA	3.02 ± 0.71 aA	17.76 ± 3.52 bA	19.88 ± 5.47 bA
	42	5.20 ± 1.02 aB	6.16 ± 2.10 aB	15.56 ± 4.68 bA	18.17 ± 3.04 bA
Soft tissue volume (StV, mm3)	14	33.59 ± 2.94 aA	33.20 ± 3.19 aA	50.61 ± 5.34 bA	56.88 ± 9.82 bA
	42	31.40 ± 4.00 aA	29.64 ± 3.00 aA	58.51 ± 13.1 bA	52.61 ± 13.5 bA
Material volume (MV/TV, %)	14	-	-	36.20 ± 5.71 aA	37.52 ± 5.75 aA
	42	-	-	35.99 ± 7.00 aA	33.85 ± 4.50 aA
Bone volume (BV/TV, %)	14	7.89 ± 3.54 aA	8.32 ± 1.60 aA	15.53 ± 2.38 bA	17.56 ± 4.04 bA
	42	14.42 ± 3.66 aB	16.96 ± 4.38 aB	13.44 ± 3.88 aA	17.37 ± 4.38 aA
Soft tissue volume (StV/TV, %)	14	92.10 ± 3.54 aA	91.68 ± 1.60 aA	48.27 ± 7.21 bA	44.92 ± 3.02 bA
	42	85.58 ± 3.66 aB	83.04 ± 4.38 aB	50.57 ± 9.74 bA	48.78 ± 8.16 bA

Different small letters (line comparison, BC vs. BCP vs. BT vs. BTP in each period, 14 or 42 days, a ≠ b) indicate a statistically significant difference. Different capital letters (comparison in columns, 14 vs. 42 days, in each parameter, A ≠ B) indicate a significant difference. Values: mean ± standard deviation. ANOVA followed by Tukey test and Student’s test respectively, are both at p < 0.05.