TABLE 2.
Results of tissue smear examination and serological tests (ELISA and C-ELISA) for patients clinically diagnosed with VLa
Group | No. (%) of
patientsb
|
Mean ± SD % inhibition of MAb D2 by C-ELISA | Mean ± SD OD at 405 nm by ELISA | ||
---|---|---|---|---|---|
Smear positive, serology positive | Smear negative, serology negative | Smear negative, serology positive | |||
A (n = 25) | 17 (68.0) | 4 (16.0) | 4 (16.0) | 20.7 ± 9.6 | 0.36 ± 0.18 |
B (n = 43) | 34 (79.0) | 6 (14.0) | 3 (7.0) | 39.2 ± 17.5 | 0.69 ± 0.36 |
C (n = 53) | 52 (98.1) | 1 (1.9) | 0 (0.0) | 50.8 ± 13.1 | 0.85 ± 0.24 |
Sera were assayed by C-ELISA and ELISA as described in Materials and Methods.
Smear, microscopic examination of Giemsa-stained splenic or bone marrow aspirates; serology, C-ELISA and ELISA.