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. 2022 Oct 4;27(19):6576. doi: 10.3390/molecules27196576

Table 1.

Bioactive components and bioactivities of Chinese Cordyceps.

No. Bioactive Components Pharmacological Effects Ref.
1 Adenosine Antitumor activity [5,6,7,8]
Attenuation of chronic heart failure [9]
Anti-inflammation [10,11,12,13,14]
Immunomodulatory activity [12,15]
2 Inosine Anti-inflammation [16]
3 Guanosine Seizure prevention [17]
Immunomodulatory activity [15]
4 Cordycepin Antitumor activity [18,19,20,21,22,23,24,25,26,27,28,29]
Antibacterial activity [20]
Treatment for ischemic/reperfusion (IR) injury [21]
Anti-inflammation [22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37]
Immunomodulatory activity [38,39,40]
Antioxidant activity [41,42]
Cholesterol lowering effect [43]
Anti-fibroblast activity [44]
5 Cordycepic acid Diuretic effect [45]
Attenuating postreperfusion syndrome [46]
Anti-fibrosis and anti-inflammation [47]
6 Polysaccharides Antitumor activity [48,49,50,51,52]
Immunomodulatory activity [48,53,54,55,56,57,58,59,60,61]
Anti-inflammation [56,62,63]
Antioxidant activity [61,64,65]
Antiviral activity [66]
Protective effects on kidney [67,68]
Hypoglycemic effect [69]
7 Cordymin Analgesic effect [70]
Anti-inflammation [71]
Antioxidant [71]
Hypoglycemic effect [72]
8 Cordycedipeptide A Antitumor activity [73]
9 Tryptophan Sedative hypnotic effect [74]
10 Fibrinolytic enzymes Treatment for thrombosis [75,76]
11 Ergosterol Cytotoxicity [77]
Anti-inflammation [78]
Anti-fibroblast activity [79]
Antiviral activity [80]
12 β-Sitosterol Cytotoxicity [77,81]
13 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol Cytotoxicity [77]
14 5α,8α-epidioxy-22E-ergosta-6,9(11),22-trien-3β-ol Cytotoxicity [77]
15 5α,6α-epoxy-5α-ergosta-7,22-dien-3β-ol Cytotoxicity [77]
16 H1-A Cytotoxicity [82]
17 Cordysinin A Anti-inflammatory [83]
18 Cordysinin B Anti-inflammatory [83]
19 Cordysinin C Anti-inflammatory [83]
20 Cordysinin D Anti-inflammatory [83]
21 Cordysinin E Anti-inflammatory [83]