Table 39.

Hypoglycemic activity of the compounds (ad21–ad22) using a streptozotocin-induced diabetic model in rats.

Comp.	Dose (mg/kg Body wt.)	% Reduction, Plasma Glucose (mg/dL) (mean ± SEM)
ad21	10/30/50	39.83 ± 0.29/44.62 ± 0.32/52.81 ± 0.32
ad22	10/30/50	36.76 ± 0.66/43.14 ± 0.35/49.99 ± 0.62
Rosiglitazone	10/30/50	38.57 ± 0.25/14.83 ± 0.18/12.74 ± 0.16