Table 46.
Antidiabetic potential of the compounds (ad36–ad39) in streptozotocin-induced diabetes in rats.
| Comp. (mg/kg Body wt.) |
Blood Glucose Level (mg/dL) | |||
|---|---|---|---|---|
| 0-Day | 3-Day | 7-Day | 10-Day | |
| ad36 | 87 ± 4.31 | 429 ± 7.77 | 246.66 ± 13.78 | 112 ± 10.13 |
| ad37 | 80 ± 4.31 | 416 ± 7.77 | 240.66 ± 13.78 | 117 ± 10.13 |
| ad38 | 85 ± 5.22 | 425 ± 9.34 | 233.52 ± 19.15 | 119 ± 18.54 |
| ad39 | 82 ± 5.22 | 418 ± 9.34 | 232.52 ± 19.15 | 120 ± 18.54 |
| Glibenclamide | 89 ± 5.34 | 411 ± 13.11 | 227.45 ± 10.38 | 109 ± 13.16 |
(N = 10) All data are given as mean ± SEM analyzed by one-way analysis of variance (ANOVA) followed by the Tukey–Kramer multiple comparison test; p < 0.001.