Table 47.
Antidiabetic potential of the compounds (ad40–ad41) using the alloxan-induced model in rats.
| Comp. | Mean ± SEM Blood Glucose Level (mg/dL) | % Reduction in Blood Glucose Level after 14 Days | ||||
|---|---|---|---|---|---|---|
| 0 h | 3 h | 6 h | 24 h | 14 days | ||
| ad40 | 355 ± 24.59 | 322.8 ± 24.10 | 253.8 ± 23.45 | 231.4 ± 23.48 | 123 ± 18.7 | 65.35 |
| ad41 | 376.4 ± 21.00 | 342.8 ± 21.58 | 315.2 ± 21.66 | 276 ± 21.79 | 146.4 ± 20.5 | 61.10 |
| Metformin | 441.8 ± 18.71 | 399.4 ± 17.72 | 289.4 ± 18.46 | 219.6 ± 18.40 | 112.8 ± 16.84 | 73.83 |
| Pioglitazone | 402.2 ± 28.7 | 363.4 ± 26.08 | 302.4 ± 26.87 | 232.2 ± 20.53 | 123.8 ± 16.94 | 69.22 |