Table 49.

Antidiabetic potential of the compounds (ad44–ad46) based on α-amylase and α-glucosidase inhibitory studies.

Comp.	C log P (Lipophilicity)	MR (Molar Refractivity)	% Inhibition (250 µg/mL)
			α-Amylase	α-Glucosidase
ad44	6.45	123	37.04	36
ad45	5.63	116.9	36.18	35.2
ad46	6.49	125.34	33.05	32.2
Acarbose	−6.6	141	43.05	40.91