Table 2.

Relationship between aquaporin 3 (AQP3) and aquaporin 4 (AQP4) and clinical-/pathological features of patients diagnosed with lung adenocarcinoma (ADC) in this study.

	AQP3 Score					AQP4 Membrane Score					AQP4 Nuclear Score
Variables	Low		High		p-Value	Low		High		p-Value	Low		High		p-Value
	n	(%)	n	(%)		n	(%)	n	(%)		n	(%)	n	(%)
Mean Age ±SD (years)	64.6 ± 8.9		60.3 ± 6.5		0.017	61.6 ± 7.5		64.5 ± 9.9		0.38	62.6 ± 8.2		61.2 ± 7.3		0.44
Gender
Female	8	(29)	19	(37)	0.44	24	(33)	3	(50)	0.40	15	(44)	12	(27)	0.11
Male	20	(71)	32	(63)		49	(67)	3	(50)		19	(56)	33	(73)
CS
I–II	3	(10)	6	(12)	0.39	7	(10)	2	(33)	0.21	6	(18)	3	(7)	0.31
III	8	(29)	8	(16)		15	(20)	1	(17)		6	(17)	10	(22)
IV	17	(61)	37	(72)		51	(70)	3	(50)		22	(65)	32	(71)
T
T1	8	(32)	4	(9)	0.06	10	(15)	2	(50)	0.20	6	(21)	6	(14)	0.70
T2	7	(28)	22	(48)		27	(40)	2	(50)		13	(45)	16	(38)
T3	2	(8)	2	(4)		4	(6)	0	(0)		1	(3)	3	(7)
T4	8	(32)	18	(39)		26	(39)	0	(0)		9	(31)	17	(41)
N
N0	2	(7)	8	(16)	0.74	8	(11)	2	(33)	0.046	7	(21)	3	(7)	0.07
N1	3	(11)	4	(8)		5	(7)	2	(33)		5	(15)	2	(5)
N2	14	(52)	24	(48)		37	(52)	1	(17)		14	(43)	24	(54)
N3	8	(30)	14	(28)		21	(30)	1	(17)		7	(21)	15	(34)
M
M0	11	(39)	15	(29)	0.37	22	(30)	4	(67)	0.07	13	(38)	13	(29)	0.38
M1	17	(61)	36	(71)		51	(70)	2	(33)		21	(62)	32	(71)
Intention to treat
radical	8	(30)	11	(22)	0.43	16	(22)	3	(50)	0.13	9	(27)	10	(23)	0.70
palliative	19	(70)	40	(78)		56	(78)	3	(50)		25	(73)	34	(77)

±SD—standard deviation; low AQP—0–2 scores, high AQP—3–9 scores.