Table 4.
Associations across tertiles of Mediterranean diet score and serum Klotho levels in subgroups.
| Tertile 1 of 1 MDS |
Tertile 2 of MDS |
Tertile 3 of MDS |
||
|---|---|---|---|---|
| Sorted by sex | ||||
| Men | ||||
| Model 1 | β coefficient (95% CI) |
Ref. | 26.62 (4.18, 49.05) |
43.48 (20.39, 66.56) |
| p value | Ref. | 0.020 | <0.001 | |
| Model 2 | β coefficient (95% CI) |
Ref. | 29.73 (7.34, 52.13) |
49.59 (26.45, 72.73) |
| p value | Ref. | 0.009 | <0.001 | |
| Model 3 | β coefficient (95% CI) |
Ref. | 27.81 (5.47, 50.16) |
45.31 (22.16, 68.47) |
| p value | Ref. | 0.015 | <0.001 | |
| Women | ||||
| Model 1 | β coefficient (95% CI) |
Ref. | 41.01 (13.34, 68.69) |
40.28 (12.63, 67.94) |
| p value | Ref. | 0.004 | 0.004 | |
| Model 2 | β coefficient (95% CI) |
Ref. | 45.34 (17.79, 72.89) |
45.01 (17.43, 72.59) |
| p value | Ref. | 0.001 | 0.001 | |
| Model 3 | β coefficient (95% CI) |
Ref. | 43.22 (15.75, 70.69) |
41.23 (13.67, 68.79) |
| p value | Ref. | 0.002 | 0.003 | |
| Sorted by age | ||||
| <65 years old | ||||
| Model 1 | β coefficient (95% CI) |
Ref. | 33.44 (12.83, 54.05) |
48.38 (27.29, 69.48) |
| p value | Ref. | 0.001 | <0.001 | |
| Model 2 | β coefficient (95% CI) |
Ref. | 31.58 (11.01, 52.15) |
45.22 (24.09, 66.35) |
| p value | Ref. | 0.003 | <0.001 | |
| Model 3 | β coefficient (95% CI) |
Ref. | 30.59 (10.09, 51.09) |
40.19 (19.07, 61.32) |
| p value | Ref. | 0.003 | <0.001 | |
| ≥65 years old | ||||
| Model 1 | β coefficient (95% CI) |
Ref. | 55.30 (20.99, 89.62) |
55.75 (21.85, 89.65) |
| p value | Ref. | 0.002 | 0.001 | |
| Model 2 | β coefficient (95% CI) |
Ref. | 53.87 (19.54, 88.21) |
52.40 (18.43, 86.38) |
| p value | Ref. | 0.002 | 0.003 | |
| Model 3 | β coefficient (95% CI) |
Ref. | 51.03 (16.68, 85.38) |
49.61 (15.54, 83.68) |
| p value | Ref. | 0.004 | 0.004 | |
| Sorted by BMI | ||||
| BMI < 30 | ||||
| Model 1 | β coefficient (95% CI) |
Ref. | 29.98 (6.66, 53.32) |
40.56 (16.93, 64.19) |
| p value | Ref. | 0.012 | 0.001 | |
| Model 2 | β coefficient (95% CI) |
Ref. | 31.09 (7.86, 54.31) |
40.98 (17.31, 64.66) |
| p value | Ref. | 0.009 | 0.001 | |
| Model 3 | β coefficient (95% CI) |
Ref. | 27.93 (4.74, 51.11) |
36.67 (12.97, 60.38) |
| p value | Ref. | 0.018 | 0.002 | |
| BMI ≥ 30 | ||||
| Model 1 | β coefficient (95% CI) |
Ref. | 46.82 (19.67, 73.97) |
53.69 (26.25, 81.13) |
| p value | Ref. | 0.001 | <0.001 | |
| Model 2 | β coefficient (95% CI) |
Ref. | 45.52 (18.42, 72.61) |
54.14 (26.68, 81.59) |
| p value | Ref. | 0.001 | <0.001 | |
| Model 3 | β coefficient (95% CI) |
Ref. | 46.29 (19.27, 73.31) |
51.86 (24.46, 79.26) |
| p value | Ref. | 0.001 | <0.001 | |
1 MDS: Mediterranean diet adherence score. Model 1 = unadjusted. Model 2 = adjusted for age, sex, body mass index, and race/ethnicity. Model 3 = Model 2 + adjusted for history of angina, congestive heart failure, coronary heart disease, diabetes mellitus, hypertension, and smoking history.