Table I.

Summary of AOPAGA cases

First author (year)	Patient (age, sex)	GA location(s)∗	Systemic symptoms	Successful treatment	Significant Comorbidities
Barksdale SK (1994)6	75, male	Fingers†	Not reported	Not reported	Lymphoma
Barksdale SK (1994)6	66, female	Fingertips‡	Not reported	Not reported	Lymphoma
Barksdale SK (1994)6	60, female	Dorsal hands	Not reported	Not reported	Lymphoma
Brey NV (2006)2	42, female	Hands§, legs, feet	Arthralgias of knees and ankles	Hydroxychloroquine sulfate	None
Brey NV (2006)2	50, female	Lateral hands, dorsal hands	None	Intralesional triamcinolone, fluticasone propionate cream, nicotinamide-folic acid-zinc oxide combination	Not reported
Brey NV (2006)2	48, female	Dorsal hands, marginal hands, wrists, upper and lower extremities, trunk, occipital scalp	Diffuse arthralgias	Hydroxychloroquine sulfate, hydrocortisone acetate/pramoxine, hydrochloride lotion	Not reported
Brey NV (2006)2	65, female	Upper and lower palms	None	Prednisone, betamethasone dipropionate ointment	Not reported
Haushalter K (2007)7	36, female	Palms, fingertips	None	Not reported	None
Spencer B (2007)8	72, female	Palms	None	Dapsone	Not reported
Gutte R (2012)3	Patient 1‖	Palms	None	Not reported	Not reported
Gutte R (2012)3	Patient 2‖	Palms	None	Not reported	Not reported
Gutte R (2012)3	Patient 3‖	Palms	None	Not reported	Not reported
Gutte R (2012)3	Patient 4‖	Palms	None	Not reported	Not reported
Huh JW (2016)4	57, female	Fingers§, legs	Febrile sensations, myalgia, back pain	None identified¶	None
Sonthalia S (2014)5	44, male	Palms, soles	None	Clobetasol ointment	None
Rai T (2017)9	55, female	Palms, soles	None	Prednisone, clobetasol, levocetirizine	Not reported
Hsing MT (2018)10	37, female	Dorsal foot	Migrating joint pain, myalgia	Prednisone, fluocinonide cream	IDA, Meniere's disease
Ahmad FS (2022) •This case report.	52, female	Palms, fingertips	Arthralgias	Prednisone	IDA, multinodular goiter, GERD, migraines, TIA, osteopenia

AOPAGA, Acute-onset, painful, acral granuloma annulare; GA, granuloma annulare; GERD, gastroesophageal reflux disease; IDA, iron-deficiency anemia; TIA, transient ischemic attack.

^∗Glabrous/volar skin is highlighted in Bold.

^†Fingers were assumed to be acral but not necessarily glabrous/volar (eg, palms/soles).

^‡Fingertip and lateral hand lesions are presumed to be on glabrous/volar hand (ie, equivalent to palms/soles).

^§Images included lesions on palmar/volar/glabrous skin.

^‖Individual patient information (eg, age, sex) was not available in this case series.

^¶Intermittent treatment with oral prednisolone did not effectively manage this patient’s AOPAGA as new cutaneous lesions persistently developed.