Table 4.
Ventilatory and Oxygenation Parameters Among 47 Pregnant Patients Requiring IMV Because of COVID-19 and Differences Between Survivors and Nonsurvivors in 21 ICUs in Argentina and Colombia During 2021
| Variable | All (n = 47) | Survivors (n = 38) | Nonsurvivors (n = 9) | P Value |
|---|---|---|---|---|
| Pao2 to Fio2 ratio before IMV (< 2 h) | 121 (86.5-162.2) | 123.5 (87.7-174) | 102.5 (90-129) | .20 |
| SpO2 before IMV, % | 90 (88-94) | 91 (90-95) | 89 (88-90) | .055 |
| Pao2 to Fio2 ratio on IMV day 0 (< 2 h) | 142 (110-176) | 147.5 (120-176) | 120 (100-142) | .17 |
| Pao2 to Fio2 ratio | ||||
| Day 2 | 200 (139-232.2) | 203 (157-230) | 144 (105-237) | .31 |
| Day 7 | 183 (141.75-235.5) | 186 (168-236) | 100 (80-188) | .08 |
| PEEP, cm H2O | ||||
| Day 0 | 11.1 ± 2.7 | 11 ± 2.4 | 11.8 ± 3.8 | .45 |
| Day 2 | 11 ± 3 | 10.7 ± 2.6 | 11.8 ± 4 | .31 |
| Day 7 | 10.2 ± 2.7 | 9.9 ± 2.4 | 11.8 ± 3.5 | .10 |
| PP, cm H2O | ||||
| Day 0 | 24.3 ± 4.5 | 23.7 ± 4.5 | 26.8 ±3.9 | .062 |
| Day 2 | 23.8 ± 6.4 | 22.7 ± 5.7 | 29.2 ± 7.1 | .011 |
| Day 7 | 25.1 ± 5.9 | 23.7 ± 4.7 | 31.8 ± 7.2 | .001 |
| SC, mL/cm H2O | ||||
| Day 0 | 31 (26-40) | 32.5 (26-41) | 27 (23-38) | .48 |
| Day 2 | 33 (23.2-42) | 33 (24-42) | 27 (21-40) | .75 |
| Day 7 | 29 (23.7-38) | 30 (24-38) | 29 (21-34.5) | .83 |
| DP, cm H2O | ||||
| Day 0 | 12.5±3.3 | 12.1 ± 3.5 | 14.1 ±2.1 | .10 |
| Day 2 | 12.6 ± 4.3 | 12.1 ± 4 | 15.3 ± 4.8 | .069 |
| Day 7 | 13.8 ± 4.8 | 12.7 ± 3.7 | 19.3 ± 4.1 | .000 |
Data are presented as No. (%), mean ± SD, or median (interquartile range), unless otherwise indicated. DP = driving pressure; IMV = invasive mechanical ventilation; PEEP = positive-end expiratory pressure; PP = plateau pressure; SC = static compliance; SpO2 = peripheral oxygen saturation.