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. 2022 Oct 10;77:100115. doi: 10.1016/j.clinsp.2022.100115

Fig. 1.

Fig. 1

Expression characteristics of miR-135a-5p in tissues of BC patients and BC cells. (A‒C) The microarray datasets GSE80038, GSE45666 and GSE38167 were downloaded from the GEO database to analyze the expression differences of miRNA, and the volcano map was used to display the differentially expressed miRNAs in the BC samples vs. normal tissue samples. (D, E) The expression of miR-135a-5p in the cancer tissues and normal tissues of 49 BC patients was detected by qRT-PCR. (F) ROC curve analysis showed the diagnostic accuracy of miR-135a-5p. (G) OncomiR database was used to analyze the relationship between the expression of miR-135a-5p and the overall survival of patients with BC. *p < 0.05, ** p < 0.01, and *** p < 0.001.