. 2022 Oct 8;8(10):e10988. doi: 10.1016/j.heliyon.2022.e10988

Table 4.

Peripheral blood serological test role in the final diagnosis.

Final diagnosis		Total N = 86	Specific IgG value IU/ml (median; IQR)	Specific IgM value (median; IQR)	Specific IgG positivity (N, %)		Specific IgM positivity (N, %)		Specific PCR positivity (N, %)
Final diagnosis		Total N = 86	Specific IgG value IU/ml (median; IQR)	Specific IgM value (median; IQR)	Positive	Negative	Positive	Negative	Positive	Negative
Toxoplasmosis^a
	Yes	12 (14%)	3953; 2707-19,562^∗	0.2; 0-2-0.4	11/75 (15%)	0/75 (0%)	1/70 (1.5%)	9/70 (13%)	2/86 (2.5%)	10/86 (11.5%)
	No	74 (86%)	428; 82-1807	0.3; 0.2-0.4	51/75 (68%)	13/75 (17%)	3/70 (4%)	57/70 (81.5%)	1/86 (1%)	73/86 (85%)
Rubella^a
	Yes	2 (2.5%)	43; 27-60	NA	2/71 (3%)	0/71 (0%)	0/65 (0%)	1/65 (1.5%)	2/86 (2.5%)	0/86 (0%)
	No	84 (97.5%)	70; 20-216	0.3; 0.2-0.3	57/71 (80%)	12/71 (17%)	4/65 (6%)	60/65 (92.5%)	1/86 (1%)	83/86 (96.5%)
CMV^a
	Yes	4 (5%)	1407; 356-2457	0.85; 0–1.7	2/74 (3%)	0/74 (0%)	1/68 (1.5%)	1/68 (1.5%)	3/86 (3.5%)	1/86 (1%)
	No	82 (95%)	210; 102-408	0.3; 0.2-0.4	68/74 (92%)	4/74 (5%)	5/68 (7.5%)	61/68 (90%)	1/86 (1%)	81/86 (94.5%)
HSV (for HSV1 serology)^a
	Yes	2 (2.5%)	4.2; (3.7–4.7)	0.3; (0.3–0.4)	2/73 (3%)	0/73 (0%)	0/72 (0%)	2/72 (2.5%)	0/86 (0%)	2/86 (2.5%)
	No	84 (97.5%)	2.5; (0.4–4)	0.4 (0.3–0.6)	49/73 (67%)	22/73 (30%)	4/72 (5.5%)	66/72 (92%)	0/86 (0%)	84/86 (97.5%)
HSV (for HSV2 serology)^a
	Yes	2 (2.5%)	0.2; (0.2–0.3)	0.1; 0.1-0.1	0/71 (0%)	2/71 (3%)	0/70 (0%)	2/70 (3%)	0/86 (0%)	2/86 (2.5%)
	No	84 (97.5%)	0.2; (0.2–0.3)	0.3; 0.2-0.5	7/71 (10%)	62/71 (87%)	4/70 (6%)	64/70 (91%)	0/86 (0%)	84/86 (97.5%)

^∗

p value < 0.0001; NA data is not available.

We exclude unavailable data and indeterminate results. Toxoplasma IgG N = 75, toxoplasma IgM N = 70, rubella IgG N = 71, rubella IgM N = 65, CMV IgG N = 74, CMV IgM N = 68, HSV1 IgG N = 73, HSV1 IgM N = 72, HSV2 IgG N = 71, HSV2 IgM N = 70.