TABLE 2.
Case reports on eye rubbing-related keratoconus.
| Author(s) | Method | Sample size | Finding |
|---|---|---|---|
| Weed et al. (2008) | Prospective observational study | n = 200 | Forty-eight percent of subjects reported significant eye rubbing, and there was a statistically significant difference (two samples t-test p = 0.018) between keratoconus and control groups |
| Bawazeer et al. (2000) | Case-control study | n = 120 | The most significant cause of keratoconus is eye rubbing. Atopy may contribute to keratoconus but most probably via eye rubbing associated with the itch of atopy |
| Bral and Termote, (2017) | Case report | n = 1 | Unilateral keratoconus described in a patient with the medical history revealed a habit of chronic eye rubbing only in one eye |
| Yusuf and Salmon (2016) | Case report | n = 1 | Keratoconus is described in a patient with obsessive–compulsive eye rubbing in the periocular contact dermatitis and allergic eye disease |
| Panikkar et al. (2016) | Case report | n = 1 | Keratoconus described in a patient with obsessive–compulsive eye rubbing |
| Gunes et al. (2015) | Case report | n = 1 | Keratoconus described in a 4-year-old patient with obsessive–compulsive eye rubbing |
| Panahi-Bazaz et al. (2014) | Case report | n = 1 | Keratoconus described in a 7-year-old patient with obsessive–compulsive eye rubbing |
| Kandarakis et al. (2011) | Case report | n = 1 | Keratoconus is described in a patient with obsessive–compulsive eye rubbing in the context of Tourette syndrome |