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. 2022 Oct 3;13:1018748. doi: 10.3389/fmicb.2022.1018748

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Copyright © 2022 Xiao, Zhang, Wang, Zhao, Xu, Chen, Tan, Sun, Huang and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of the therapeutic effect of chimeric IgG/IgA produced by CHO cell line. Piglets feces (A) and intestinal tract (B) in group 2 (one day after IgG/IgA treatment) and 3 (no antibody treatment). (C) The PEDV RNA copies in the feces of piglets, the error bars indicated standard deviation. Data were analyzed using two-way ANOVA by time. (D) IHC and HE assay of the piglets in group 1 (unchallenged), 2 (IgG/IgA treatment) and 3 (no antibody treatment). dpi, day-post-infection.