Table 1.
Summary of transcription factors and epigenetic factors activated by LLPS.
| Protein | Cell type | Cellular mechanisms | Reference |
|---|---|---|---|
| YAP, TAZ, TEAD | Lung adenocarcinoma model, melanoma |
Induced by IFNγ for anti-PD-1 resistance |
77 |
| Breast cancer | Activation of YAP signaling | 78, 79 | |
| ERα | Breast cancer | Enhancer activation | 80 |
| AR | Prostate cancer | Collaboration with FOXA1 and OCT4 |
81 |
| FET fusion | Ewing sarcoma | Recruit BAF complex | 82, 83 |
| NUP98 fusion | Pediatric AML | Chromatin looping | 84, 85 |
| β-catenin | murine embryonic stem cells (ESCs) |
Complex with Mediators | 86 |