Table 2.
Effectiveness in the pharmacotherapeutics variables after the application of the person-centered prescription model.
| Variable |
Control (n = 42)a |
Intervention (n = 39)a |
Mean difference. Change between groups | CI | p-Value | ||||
|---|---|---|---|---|---|---|---|---|---|
| Admission | Discharge | Difference | Admission | Discharge | Difference | ||||
| No. of regular medications, mean (SD) | 8.05 (3.13) | 7.98 (3.46) | −0.07 (2.37) | 8.46 (3.27) | 6.72 (2.76) | −1.74 (2.75) | 1.67 (0.57) | 0.54–2.81 | 0.007* |
| STOPP Frail-defined PIMs, mean (SD) | 1.74 (1.38) | 1.29 (1.31) | −0.45 (0.80) | 1.69 (1.36) | 0.15 (0.37) | −1.54 (1.29) | 1.09 (0.24) | 0.60–1.57 | < 0.001* |
| DBI, mean (SD) | 1.00 (0.70) | 1.02 (0.64) | 0.02 (0.42) | 1.27 (0.82) | 1.01 (0.71) | −0.26 (0.63) | 0.28 (0.12) | −0.04–0.52 | 0.010* |
| Total drug-drug interactions, mean (SD) | 3.24 (3.07) | 3.31 (3.58) | 0.70 (3.60) | 3.79 (3.25) | 2.28 (2.67) | −1.51 (2.15) | 1.58 (0.66) | 0.26–2.90 | < 0.001* |
| MRCI, mean (SD) | 27.18 (12.70) | 28.71 (13.17) | 1.53 (9.02) | 29.28 (11.33) | 23.68 (10.02) | −5.60 (9.18) | 7.14 (2.02) | 3.11–11.17 | 0.001* |
CI, confidence interval; DBI, drug burden index; MRCI, medication regimen complexity index; PIM, potentially inappropriate medications; SD, standard deviation.
aOnly participants who were alive at hospital discharge were included.
*p < 0.05.