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Activity of the main placental enzymes involved in steroidogenesis in the PE and control groups.
| Enzyme involved | PE | Control | p value |
|---|---|---|---|
| Metabolite’s ratio | (n = 5) | (n = 5) | |
| HSD11B1/HSD11B2 | |||
| Cortisol/Cortisone | 2.64e-2 | 5.05e-2 | 0.193 |
| HSD17B8/HSD17B6 | |||
| T/A4 | 4.39 | 1.22 | 0.154 |
| CYP19A1 | |||
| E1/A4 | 48.77 | 54.39 | 0.421 |
Control, normal pregnancy; PE, preeclamptic pregnancy; NS, not significant. Values are expressed as the means ± SDs. E1, estrone; A4, androstenedione.
