Table 3.

Multivariable linear regression analysis of relationship between logarithmic urinary IL-18 and cf-PWV.

Variables	Model 1		Model 2		Model 3
	β	p	β	p	β	p
UIL-18 a	0.098	<0.001	0.077	0.005	0.062	0.037
Age	0.007	<0.001	0.006	0.002	0.004	0.028
Male	0.020	0.551	0.072	0.056	0.035	0.415
BMI			0.001	0.837	0.001	0.963
Duration of T2D			0.006	0.017	0.006	0.028
Hypertension			0.130	<0.001	0.098	0.007
Hb			−0.002	0.041	−0.002	0.122
Albumin			0.001	0.843	0.003	0.418
TC			0.027	0.019	0.012	0.388
HDL			0.027	0.649	0.054	0.400
eGFR					−0.001	0.389
UACR ≥ 30 mg/g					0.096	0.012
SIL-18 a					0.026	0.499

eGFR, estimated glomerular filtration rate; FBG, fast blood glucose; Hb, hemoglobin; SIL-18, serum interleukin-18; TC, total cholesterol; T2D, type 2 diabetes; UACR, urinary albumin-to-creatinine ratio; UIL-18, urinary interleukin-18.

a, Urinary and serum IL-18 levels were analyzed as naturally logarithmically transformed values.

Model 1: Age and gender. Model 2: Model 1 and traditional arterial stiffness risk factors (BMI, duration of T2D, hypertension, Hb, albumin, TC, and HDL). Model 3: Model 2 and UACR, eGFR, and serum IL-18.