Table 5.
Statistical analysis of reviewed studies for PD.
| Metabolite | Materials | Number of studies | SMD | 95%CI | I2(%) | P-value for heterogenicity |
|---|---|---|---|---|---|---|
| TRP | CSF | 6 | -0.05 | (-0.40, 0.31) | 48.0 | 0.087 |
| Blood (serum/plasma) | 4 | -0.77 | (-1.24, -0.30) | 74.9 | 0.008 | |
| KYN | CSF | 5 | -0.19 | (-1.17, 0.79) | 88.6 | 0.000 |
| Blood (serum/plasma) | 4 | 0.28 | (-0.44, 0.99) | 86.2 | 0.000 | |
| KYNA | Blood (serum/plasma) | 4 | -0.14 | (-1.07, 0.80) | 89.6 | 0.000 |
| AA | Blood (serum/plasma) | 3 | 0.38 | (-0.40, 1.16) | 80.9 | 0.005 |
| 5HIAA | CSF | 3 | -0.42 | (-1.23, 0.39) | 72.9 | 0.025 |
| 3-HK | CSF | 5 | -0.97 | (-2.28, 0.34) | 92.6 | 0.000 |
| Blood (serum/plasma) | 3 | -0.01 | (-0.41, 0.39) | 48.1 | 0.146 |